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Neural activity promotes long distance, target-specific regeneration of adult retinal axons
Axons in the mammalian central nervous system (CNS) fail to regenerate after injury. Here we show that if retinal ganglion cell (RGC) activity is increased by visual stimulation or using chemogenetics, their axons regenerate. We also show that if enhancement of neural activity is combined with eleva...
Autores principales: | Lim, Jung-Hwan A., Stafford, Benjamin K., Nguyen, Phong L., Lien, Brian V., Wang, Chen, Zukor, Katherine, He, Zhigang, Huberman, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708130/ https://www.ncbi.nlm.nih.gov/pubmed/27399843 http://dx.doi.org/10.1038/nn.4340 |
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