Role of P-glycoprotein on CD69(+)CD4(+) cells in the pathogenesis of proliferative lupus nephritis and non-responsiveness to immunosuppressive therapy

INTRODUCTION: P-glycoprotein (P-gp) expression on activated lymphocytes in systemic lupus erythematosus (SLE) plays a role in active efflux of intracellular drugs, resulting in drug resistance. The role of P-gp-expressing lymphocytes in the pathogenesis of SLE remains unclear. The aim of this study...

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Detalles Bibliográficos
Autores principales: Tsujimura, Shizuyo, Adachi, Tomoko, Saito, Kazuyoshi, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RMD Open 2017
Materias:
Lupus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708311/
https://www.ncbi.nlm.nih.gov/pubmed/29225917
http://dx.doi.org/10.1136/rmdopen-2016-000423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708311/
https://www.ncbi.nlm.nih.gov/pubmed/29225917
http://dx.doi.org/10.1136/rmdopen-2016-000423

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