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To cage or to be caged? The cytotoxic species in ruthenium-based photoactivated chemotherapy is not always the metal
In metal-based photoactivated chemotherapy (PACT), two photoproducts are generated by light-triggered photosubstitution of a metal-bound ligand: the free ligand itself and an aquated metal complex. By analogy with cisplatin, the aquated metal complex is usually presented as the biologically active s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708332/ https://www.ncbi.nlm.nih.gov/pubmed/28597879 http://dx.doi.org/10.1039/c7cc03469e |