Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6-pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF(5)-substituted oxindoles with a range of aldehydes. The resulting products were characterized by X-ray crystallography studies and were...

Descripción completa

Detalles Bibliográficos
Autores principales: Sansook, Supojjanee, Ocasio, Cory A., Day, Iain J., Tizzard, Graham J., Coles, Simon J., Fedorov, Oleg, Bennett, James M., Elkins, Jonathan M., Spencer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708334/
https://www.ncbi.nlm.nih.gov/pubmed/28984325
http://dx.doi.org/10.1039/c7ob02289a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708334/
https://www.ncbi.nlm.nih.gov/pubmed/28984325
http://dx.doi.org/10.1039/c7ob02289a

Ejemplares similares