Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy

A photocrosslinkable protein G variant was used as an adapter protein to covalently and site-specifically conjugate an antibody and an Fc-fusion protein to an oligonucleotide. This modular approach enables straightforward decoration of DNA nanostructures with complex native proteins while retaining...

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Detalles Bibliográficos
Autores principales: Rosier, Bas J. H. M., Cremers, Glenn A. O., Engelen, Wouter, Merkx, Maarten, Brunsveld, Luc, de Greef, Tom F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708335/
https://www.ncbi.nlm.nih.gov/pubmed/28617516
http://dx.doi.org/10.1039/c7cc04178k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708335/
https://www.ncbi.nlm.nih.gov/pubmed/28617516
http://dx.doi.org/10.1039/c7cc04178k

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