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Bypassing the proline/thiazoline requirement of the macrocyclase PatG
Biocatalysis is a fast developing field in which an enzyme's natural capabilities are harnessed or engineered for synthetic chemistry. The enzyme PatG is an extremely promiscuous macrocyclase enzyme tolerating both non-natural amino acids and non-amino acids within the substrate. It does, howev...
Autores principales: | Oueis, E., Stevenson, H., Jaspars, M., Westwood, N. J., Naismith, J. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708355/ https://www.ncbi.nlm.nih.gov/pubmed/29090689 http://dx.doi.org/10.1039/c7cc06550g |
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