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Natural products modulating the hERG channel: heartaches and hope

Covering: 1996–December 2016 The human Ether-à-go-go Related Gene (hERG) channel is a voltage-gated potassium channel playing an essential role in the normal electrical activity in the heart. It is involved in the repolarization and termination of action potentials in excitable cardiac cells. Mutati...

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Detalles Bibliográficos
Autores principales: Kratz, Jadel M., Grienke, Ulrike, Scheel, Olaf, Mann, Stefan A., Rollinger, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708533/
https://www.ncbi.nlm.nih.gov/pubmed/28497823
http://dx.doi.org/10.1039/c7np00014f