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Structural analysis of human glycoprotein butyrylcholinesterase using atomistic molecular dynamics: The importance of glycosylation site ASN(241)

Human butyrylcholinesterase (BChE) is a glycoprotein capable of bioscavenging toxic compounds such as organophosphorus (OP) nerve agents. For commercial production of BChE, it is practical to synthesize BChE in non–human expression systems, such as plants or animals. However, the glycosylation profi...

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Detalles Bibliográficos
Autores principales: Bernardi, Austen, Kirschner, Karl N., Faller, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708630/
https://www.ncbi.nlm.nih.gov/pubmed/29190644
http://dx.doi.org/10.1371/journal.pone.0187994