3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT

Pancreatic cancer, one of the deadliest cancers, is characterized by high rates of metastasis and intense desmoplasia, both of which are associated with changes in fibrillar type I collagen composition and microstructure. Epithelial to mesenchymal transition (EMT), a critical step of metastasis, als...

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Detalles Bibliográficos
Autores principales: Puls, T. J., Tan, Xiaohong, Whittington, Catherine F., Voytik-Harbin, Sherry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708668/
https://www.ncbi.nlm.nih.gov/pubmed/29190794
http://dx.doi.org/10.1371/journal.pone.0188870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708668/
https://www.ncbi.nlm.nih.gov/pubmed/29190794
http://dx.doi.org/10.1371/journal.pone.0188870

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