Type I interferon signaling restrains IL-10R(+) colonic macrophages and dendritic cells and leads to more severe Salmonella colitis

Type I interferons (IFNα, IFNβ) are key regulators of innate and adaptive immunity, modulating the severity of both viral and bacterial infections. While type I IFN signaling leads to improved outcomes in viral infections, its role in bacterial infections is more contextual and depends on the specif...

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Detalles Bibliográficos
Autores principales: Stefan, Kailyn L., Fink, Avner, Surana, Neeraj K., Kasper, Dennis L., Dasgupta, Suryasarathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708670/
https://www.ncbi.nlm.nih.gov/pubmed/29190678
http://dx.doi.org/10.1371/journal.pone.0188600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708670/
https://www.ncbi.nlm.nih.gov/pubmed/29190678
http://dx.doi.org/10.1371/journal.pone.0188600

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