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Role of cis-trans proline isomerization in the function of pathogenic enterobacterial Periplasmic Binding Proteins

Periplasmic Binding Proteins (PBPs) trap nutrients for their internalization into bacteria by ABC transporters. Ligand binding triggers PBP closure by bringing its two domains together like a Venus flytrap. The atomic determinants that control PBP opening and closure for nutrient capture and release...

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Detalles Bibliográficos
Autores principales: Cortes-Hernandez, Paulina, Domínguez-Ramírez, Lenin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708682/
https://www.ncbi.nlm.nih.gov/pubmed/29190818
http://dx.doi.org/10.1371/journal.pone.0188935