Synergistic role of 5-azacytidine and ascorbic acid in directing cardiosphere derived cells to cardiomyocytes in vitro by downregulating Wnt signaling pathway via phosphorylation of β-catenin

BACKGROUND: Cardiosphere derived cells (CDCs) represent a valuable source in stem cell based therapy for cardiovascular diseases, yet poor differentiation rate hinders the transplantation efficiency. The aim of this study is to check the ability of 5-Azacytidine (Aza) alone and in combination with a...

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Detalles Bibliográficos
Autores principales: Mundre, Reddy Sailaja, Koka, Pavani, Dhanaraj, Prakash, Khatri, Nitin, Vig, Sanjana, Chandramohan, Yamini, Dhanasekaran, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708695/
https://www.ncbi.nlm.nih.gov/pubmed/29190771
http://dx.doi.org/10.1371/journal.pone.0188805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708695/
https://www.ncbi.nlm.nih.gov/pubmed/29190771
http://dx.doi.org/10.1371/journal.pone.0188805

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