The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration

During development, a multi-potent group of cells known as the cranial neural crest (CNC) migrate to form craniofacial structures. Proper migration of these cells requires proteolysis of cell adhesion molecules, such as cadherins. In Xenopus laevis, preventing extracellular cleavage of cadherin-11 i...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathavan, Ketan, Khedgikar, Vikram, Bartolo, Vanessa, Alfandari, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708760/
https://www.ncbi.nlm.nih.gov/pubmed/29190819
http://dx.doi.org/10.1371/journal.pone.0188963