A non-threshold region-specific method for detecting rare variants in complex diseases

A region-specific method, NTR (non-threshold rare) variant detection method, was developed—it does not use the threshold for defining rare variants and accounts for directions of effects. NTR also considers linkage disequilibrium within the region and accommodates common and rare variants simultaneo...

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Detalles Bibliográficos
Autores principales: Hsieh, Ai-Ru, Chen, Dao-Peng, Chattopadhyay, Amrita Sengupta, Li, Ying-Ju, Chang, Chien-Ching, Fann, Cathy S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708778/
https://www.ncbi.nlm.nih.gov/pubmed/29190701
http://dx.doi.org/10.1371/journal.pone.0188566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708778/
https://www.ncbi.nlm.nih.gov/pubmed/29190701
http://dx.doi.org/10.1371/journal.pone.0188566

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