Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques

Molecular imaging of matrix metalloproteinases (MMPs) may allow detection of atherosclerotic lesions vulnerable to rupture. In this study, we develop a novel radiolabelled compound that can target gelatinase MMP subtypes (MMP2/9) with high selectivity and inhibitory potency. Inhibitory potencies of...

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Detalles Bibliográficos
Autores principales: Hakimzadeh, Nazanin, Pinas, Victorine A., Molenaar, Ger, de Waard, Vivian, Lutgens, Esther, van Eck-Smit, Berthe L. F., de Bruin, Kora, Piek, Jan J., Eersels, Jos L. H., Booij, Jan, Verberne, Hein J., Windhorst, Albert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708805/
https://www.ncbi.nlm.nih.gov/pubmed/29190653
http://dx.doi.org/10.1371/journal.pone.0187767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708805/
https://www.ncbi.nlm.nih.gov/pubmed/29190653
http://dx.doi.org/10.1371/journal.pone.0187767

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