In vivo imaging of protease activity by Probody therapeutic activation

Probody(™) therapeutics are recombinant, proteolytically-activated antibody prodrugs, engineered to remain inert until activated locally by tumor-associated proteases. Probody therapeutics exploit the fundamental dysregulation of extracellular protease activity that exists in tumors relative to heal...

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Detalles Bibliográficos
Autores principales: Wong, Kenneth R., Menendez, Elizabeth, Craik, Charles S., Kavanaugh, W. Michael, Vasiljeva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709043/
https://www.ncbi.nlm.nih.gov/pubmed/26546838
http://dx.doi.org/10.1016/j.biochi.2015.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709043/
https://www.ncbi.nlm.nih.gov/pubmed/26546838
http://dx.doi.org/10.1016/j.biochi.2015.11.003

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