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In vivo imaging of protease activity by Probody therapeutic activation
Probody(™) therapeutics are recombinant, proteolytically-activated antibody prodrugs, engineered to remain inert until activated locally by tumor-associated proteases. Probody therapeutics exploit the fundamental dysregulation of extracellular protease activity that exists in tumors relative to heal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709043/ https://www.ncbi.nlm.nih.gov/pubmed/26546838 http://dx.doi.org/10.1016/j.biochi.2015.11.003 |