The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma

Kinesin spindle protein inhibition is known to be an effective therapeutic approach in several malignancies. Filanesib (ARRY-520), an inhibitor of this protein, has demonstrated activity in heavily pre-treated multiple myeloma patients. The aim of the work herein was to investigate the activity of f...

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Detalles Bibliográficos
Autores principales: Hernández-García, Susana, San-Segundo, Laura, González-Méndez, Lorena, Corchete, Luis A., Misiewicz-Krzeminska, Irena, Martín-Sánchez, Montserrat, López-Iglesias, Ana-Alicia, Algarín, Esperanza Macarena, Mogollón, Pedro, Díaz-Tejedor, Andrea, Paíno, Teresa, Tunquist, Brian, Mateos, María-Victoria, Gutiérrez, Norma C, Díaz-Rodriguez, Elena, Garayoa, Mercedes, Ocio, Enrique M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709111/
https://www.ncbi.nlm.nih.gov/pubmed/28860344
http://dx.doi.org/10.3324/haematol.2017.168666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709111/
https://www.ncbi.nlm.nih.gov/pubmed/28860344
http://dx.doi.org/10.3324/haematol.2017.168666

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