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A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice

Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodefici...

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Detalles Bibliográficos
Autores principales: Gunawan, Merry, Her, Zhisheng, Liu, Min, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Dharmaraaja, Shubasree, Fan, Yong, Ong, Chee Bing, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Chan, Jerry Kok Yen, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709358/
https://www.ncbi.nlm.nih.gov/pubmed/29192160
http://dx.doi.org/10.1038/s41598-017-16999-7