Cargando…
A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice
Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodefici...
Autores principales: | Gunawan, Merry, Her, Zhisheng, Liu, Min, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Dharmaraaja, Shubasree, Fan, Yong, Ong, Chee Bing, Loh, Eva, Chang, Kenneth Tou En, Tan, Thiam Chye, Chan, Jerry Kok Yen, Chen, Qingfeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709358/ https://www.ncbi.nlm.nih.gov/pubmed/29192160 http://dx.doi.org/10.1038/s41598-017-16999-7 |
Ejemplares similares
-
Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model
por: Zheng, Zhiqiang, et al.
Publicado: (2017) -
Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy
por: Zhao, Yue, et al.
Publicado: (2018) -
Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection
por: Keng, Choong Tat, et al.
Publicado: (2016) -
Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics
por: Yong, Kylie Su Mei, et al.
Publicado: (2020) -
A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions
por: Mencarelli, Andrea, et al.
Publicado: (2020)