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Profiling of the transcriptional response to all-trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression

Retinoids, derivatives of vitamin A, are key physiological molecules with regulatory effects on cell differentiation, proliferation and apoptosis. As a result, they are of interest for cancer therapy. Specifically, models of breast cancer have varied responses to manipulations of retinoid signaling....

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Detalles Bibliográficos
Autores principales: Coyle, Krysta Mila, Maxwell, Selena, Thomas, Margaret Lois, Marcato, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709375/
https://www.ncbi.nlm.nih.gov/pubmed/29192143
http://dx.doi.org/10.1038/s41598-017-16687-6