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HIDEEP: a systems approach to predict hormone impacts on drug efficacy based on effect paths

Experimental evidence has shown that some of the human endogenous hormones significantly affect drug efficacy. Since hormone status varies with individual physiological states, it is essential to understand the interplay of hormones and drugs for precision medicine. Here, we developed an in silico m...

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Detalles Bibliográficos
Autores principales: Kwon, Mijin, Jung, Jinmyung, Yu, Hasun, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709390/
https://www.ncbi.nlm.nih.gov/pubmed/29192270
http://dx.doi.org/10.1038/s41598-017-16855-8