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HIDEEP: a systems approach to predict hormone impacts on drug efficacy based on effect paths
Experimental evidence has shown that some of the human endogenous hormones significantly affect drug efficacy. Since hormone status varies with individual physiological states, it is essential to understand the interplay of hormones and drugs for precision medicine. Here, we developed an in silico m...
Autores principales: | Kwon, Mijin, Jung, Jinmyung, Yu, Hasun, Lee, Doheon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709390/ https://www.ncbi.nlm.nih.gov/pubmed/29192270 http://dx.doi.org/10.1038/s41598-017-16855-8 |
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