Cargando…
Ribosomal stress and Tp53-mediated neuronal apoptosis in response to capsid protein of the Zika virus
We report here that in rat and human neuroprogenitor cells as well as rat embryonic cortical neurons Zika virus (ZIKV) infection leads to ribosomal stress that is characterized by structural disruption of the nucleolus. The anti-nucleolar effects were most pronounced in postmitotic neurons. Moreover...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709411/ https://www.ncbi.nlm.nih.gov/pubmed/29192272 http://dx.doi.org/10.1038/s41598-017-16952-8 |