CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells

The combination of genome-edited human embryonic stem cells (hESCs) and subsequent neural differentiation is a powerful tool to study neurodevelopmental disorders. Since the naïve state of pluripotency has favourable characteristics for efficient genome-editing, we optimized a workflow for the CRISP...

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Detalles Bibliográficos
Autores principales: Jacobs, Eva Z., Warrier, Sharat, Volders, Pieter-Jan, D’haene, Eva, Van Lombergen, Eva, Vantomme, Lies, Van der Jeught, Margot, Heindryckx, Björn, Menten, Björn, Vergult, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709416/
https://www.ncbi.nlm.nih.gov/pubmed/29192200
http://dx.doi.org/10.1038/s41598-017-16932-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709416/
https://www.ncbi.nlm.nih.gov/pubmed/29192200
http://dx.doi.org/10.1038/s41598-017-16932-y

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