Fine control of metal concentrations is necessary for cells to discern zinc from cobalt

Bacteria possess transcription factors whose DNA-binding activity is altered upon binding to specific metals, but metal binding is not specific in vitro. Here we show that tight regulation of buffered intracellular metal concentrations is a prerequisite for metal specificity of Zur, ZntR, RcnR and F...

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Detalles Bibliográficos
Autores principales: Osman, Deenah, Foster, Andrew W., Chen, Junjun, Svedaite, Kotryna, Steed, Jonathan W., Lurie-Luke, Elena, Huggins, Thomas G., Robinson, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709419/
https://www.ncbi.nlm.nih.gov/pubmed/29192165
http://dx.doi.org/10.1038/s41467-017-02085-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709419/
https://www.ncbi.nlm.nih.gov/pubmed/29192165
http://dx.doi.org/10.1038/s41467-017-02085-z

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