Low-dose levels of bisphenol A inhibit telomerase via ER/GPR30-ERK signalling, impair DNA integrity and reduce cell proliferation in primary PBMC

Controversy exists about the human health risk of environmental exposure to bisphenol A (BPA). Telomerase activity is emerging both as biomarker and contributing factor for age-related diseases. The effects of BPA exposure at 1–1000 nM on telomerase, DNA integrity and cell proliferation were investi...

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Detalles Bibliográficos
Autores principales: Herz, Corinna, Tran, Hoai Thi Thu, Schlotz, Nina, Michels, Karin, Lamy, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709422/
https://www.ncbi.nlm.nih.gov/pubmed/29192164
http://dx.doi.org/10.1038/s41598-017-15978-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709422/
https://www.ncbi.nlm.nih.gov/pubmed/29192164
http://dx.doi.org/10.1038/s41598-017-15978-2

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