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Low-dose levels of bisphenol A inhibit telomerase via ER/GPR30-ERK signalling, impair DNA integrity and reduce cell proliferation in primary PBMC
Controversy exists about the human health risk of environmental exposure to bisphenol A (BPA). Telomerase activity is emerging both as biomarker and contributing factor for age-related diseases. The effects of BPA exposure at 1–1000 nM on telomerase, DNA integrity and cell proliferation were investi...
Autores principales: | Herz, Corinna, Tran, Hoai Thi Thu, Schlotz, Nina, Michels, Karin, Lamy, Evelyn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709422/ https://www.ncbi.nlm.nih.gov/pubmed/29192164 http://dx.doi.org/10.1038/s41598-017-15978-2 |
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