Estrogen attenuates AGTR1 expression to reduce pancreatic β-cell death from high glucose

Chronic exposure of pancreatic β-cells to high glucose levels results in β-cell dysfunction and death. These effects can be protected by estrogen. The local pancreatic renin-angiotensin system (RAS) has been shown as a novel pathological pathway of high-glucose-induced cell death. The effect of estr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kooptiwut, Suwattanee, Wanchai, Keerati, Semprasert, Namoiy, Srisawat, Chatchawan, Yenchitsomanus, Pa-thai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709427/
https://www.ncbi.nlm.nih.gov/pubmed/29192236
http://dx.doi.org/10.1038/s41598-017-15237-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709427/
https://www.ncbi.nlm.nih.gov/pubmed/29192236
http://dx.doi.org/10.1038/s41598-017-15237-4

Ejemplares similares