Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice

The pathology of schistosome egg-induced liver granuloma, fibrosis and eventually liver scarring is complicated. CD4(+) helper T (Th) cells play critical roles in both host humoral immunity and cellular immunity against parasitic infection and immunopathology in schistosomiasis. Follicular helper T...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yanyan, Lin, Cai, Cao, Yun, Duan, Zhongliang, Guan, Zhixun, Xu, Jing, Zhu, Xing-Quan, Xia, Chaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709429/
https://www.ncbi.nlm.nih.gov/pubmed/29192177
http://dx.doi.org/10.1038/s41598-017-16783-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709429/
https://www.ncbi.nlm.nih.gov/pubmed/29192177
http://dx.doi.org/10.1038/s41598-017-16783-7

Ejemplares similares