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Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice

The pathology of schistosome egg-induced liver granuloma, fibrosis and eventually liver scarring is complicated. CD4(+) helper T (Th) cells play critical roles in both host humoral immunity and cellular immunity against parasitic infection and immunopathology in schistosomiasis. Follicular helper T...

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Detalles Bibliográficos
Autores principales:	Wang, Yanyan, Lin, Cai, Cao, Yun, Duan, Zhongliang, Guan, Zhixun, Xu, Jing, Zhu, Xing-Quan, Xia, Chaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709429/ https://www.ncbi.nlm.nih.gov/pubmed/29192177 http://dx.doi.org/10.1038/s41598-017-16783-7

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