Cargando…

Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice

The pathology of schistosome egg-induced liver granuloma, fibrosis and eventually liver scarring is complicated. CD4(+) helper T (Th) cells play critical roles in both host humoral immunity and cellular immunity against parasitic infection and immunopathology in schistosomiasis. Follicular helper T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yanyan, Lin, Cai, Cao, Yun, Duan, Zhongliang, Guan, Zhixun, Xu, Jing, Zhu, Xing-Quan, Xia, Chaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709429/ https://www.ncbi.nlm.nih.gov/pubmed/29192177 http://dx.doi.org/10.1038/s41598-017-16783-7

Ejemplares similares

Dynamics of Th9 cells and their potential role in immunopathogenesis of murine schistosomiasis
por: Zhan, Tingzheng, et al.
Publicado: (2017)

Fate tracking reveals differences between Reelin(+) hepatic stellate cells (HSCs) and Desmin(+) HSCs in activation, migration and proliferation
por: Chen, Ning, et al.
Publicado: (2023)

Ca(2+)tapulting HSCs into action
por: Guitart, Amelie V., et al.
Publicado: (2018)

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging
por: Säwen, Petter, et al.
Publicado: (2018)

Single-Cell Approaches to Deconvolute the Development of HSCs
por: Xiang, Yang, et al.
Publicado: (2021)

Human cord blood-derived primitive CD34-negative hematopoietic stem cells (HSCs) are myeloid-biased long-term repopulating HSCs
por: Matsuoka, Y, et al.
Publicado: (2015)

Gene drives for schistosomiasis transmission control
por: Maier, Theresa, et al.
Publicado: (2019)

FV Vectors as Alternative Gene Vehicles for Gene Transfer in HSCs
por: Simantirakis, Emmanouil, et al.
Publicado: (2020)

Just a Spoonful of Sugar Helps the HSCs Move ’Round
por: Kent, David G.
Publicado: (2021)

Recent progress in the effect of ferroptosis of HSCs on the development of liver fibrosis
por: Tang, Rui, et al.
Publicado: (2023)

HSCs-derived COMP drives hepatocellular carcinoma progression by activating MEK/ERK and PI3K/AKT signaling pathways
por: Li, Qing, et al.
Publicado: (2018)

Host regulation of liver fibroproliferative pathology during experimental schistosomiasis via interleukin-4 receptor alpha
por: Nono, Justin Komguep, et al.
Publicado: (2017)

Refining the migration and engraftment of short-term and long-term HSCs by enhancing homing-specific adhesion mechanisms
por: Al-Amoodi, Asma S., et al.
Publicado: (2022)

Correlation of interleukin-6-174 GC and interleukin-6-572 GC gene polymorphisms with periodontal disease in an Iranian population
por: Salman, Bahareh Nazemi, et al.
Publicado: (2016)

In Vivo Tracking and Comparison of the Therapeutic Effects of MSCs and HSCs for Liver Injury
por: Li, Qiang, et al.
Publicado: (2013)

HSCs transdifferentiate primarily to pneumonocytes in radiation-induced lung damage repair
por: Li, Lei, et al.
Publicado: (2021)

Hyperleukocytic Acute Leukemia Circulating Exosomes Regulate HSCs and BM-MSCs
por: Yang, Yanmei, et al.
Publicado: (2021)

KRT17 Promotes the Activation of HSCs via EMT in Liver Fibrosis
por: Chen, Jing, et al.
Publicado: (2022)

Ripk3 signaling regulates HSCs during stress and represses radiation-induced leukemia in mice
por: Zhang, Lei, et al.
Publicado: (2022)

rSjP40 Inhibited the Activity of Collagen Type I Promoter via Ets-1 in HSCs
por: Li, Jing, et al.
Publicado: (2021)

Assessment of China’s contributions to the Regional Network for Asian Schistosomiasis and Other Helminth Zoonoses: a questionnaire survey
por: Li, Hong-Mei, et al.
Publicado: (2021)

Runx1 is required for progression of CD41(+) embryonic precursors into HSCs but not prior to this
por: Liakhovitskaia, Anna, et al.
Publicado: (2014)

Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging
por: Li, Dan, et al.
Publicado: (2015)

How HSCs Colonize and Expand in the Fetal Niche of the Vertebrate Embryo: An Evolutionary Perspective
por: Mahony, Christopher B., et al.
Publicado: (2019)

Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis
por: Chen, Xin, et al.
Publicado: (2018)

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro
por: Girotra, Mukul, et al.
Publicado: (2020)

Characterization of the Roles of Vimentin in Regulating the Proliferation and Migration of HSCs during Hepatic Fibrogenesis
por: Wang, Pei-Wen, et al.
Publicado: (2019)

Retracted: Hyperleukocytic Acute Leukemia Circulating Exosomes Regulate HSCs and BM-MSCs
por: Healthcare Engineering, Journal of
Publicado: (2022)

Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs
por: Xie, Xiaoqing, et al.
Publicado: (2023)

The microbiome in urogenital schistosomiasis and induced bladder pathologies
por: Adebayo, Adewale S., et al.
Publicado: (2017)

Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis
por: De Simone, Veronica, et al.
Publicado: (2015)

The Search for a Schistosomiasis Vaccine: Australia’s Contribution
por: McManus, Donald P.
Publicado: (2021)

Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs
por: Park, Sun-Mi, et al.
Publicado: (2014)

A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models
por: Hamilton, Noémie, et al.
Publicado: (2018)

Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs
por: Jeon, Hyojung, et al.
Publicado: (2021)

NAD(+) augmentation with nicotinamide riboside improves lymphoid potential of Atm(−/−) and old mice HSCs
por: Zong, Le, et al.
Publicado: (2021)

A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress
por: Cacialli, Pietro, et al.
Publicado: (2021)

A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo
por: Demel, Uta Margareta, et al.
Publicado: (2022)

CRX-527 induced differentiation of HSCs protecting the intestinal epithelium from radiation damage
por: Liu, Dongshu, et al.
Publicado: (2022)

Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution
por: Ishida, Takashi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8gtktgbtsa3qt2dcpdek6fldl7