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MicroRNA-21 regulates Osteogenic Differentiation of Periodontal Ligament Stem Cells by targeting Smad5

Human periodontal ligament stem cells (hPDLSCs) are mesenchymal stem cells (MSCs) derived from dental and craniofacial tissues that exhibit high potential for differentiation into osteoblasts. Recently, microRNAs (miRNAs) have been established to play important roles in MSC osteogenesis. In the curr...

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Detalles Bibliográficos
Autores principales: Wei, Fulan, Yang, Shuangyan, Guo, Qingyuan, Zhang, Xin, Ren, Dapeng, Lv, Tao, Xu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709498/
https://www.ncbi.nlm.nih.gov/pubmed/29192241
http://dx.doi.org/10.1038/s41598-017-16720-8