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Mineral particles stimulate innate immunity through neutrophil extracellular traps containing HMGB1
Calcium phosphate-based mineralo-organic particles form spontaneously in the body and may represent precursors of ectopic calcification. We have shown earlier that these particles induce activation of caspase-1 and secretion of IL-1β by macrophages. However, whether the particles may produce other e...
Autores principales: | Peng, Hsin-Hsin, Liu, Yu-Ju, Ojcius, David M., Lee, Chiou-Mei, Chen, Ren-Hao, Huang, Pei-Rong, Martel, Jan, Young, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709501/ https://www.ncbi.nlm.nih.gov/pubmed/29192209 http://dx.doi.org/10.1038/s41598-017-16778-4 |
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