Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction

Recently, it has been reported that human hepatocyte-like cells can be generated from fibroblasts by direct reprogramming technology. However, the conversion efficiency of human induced hepatocyte-like cells (hiHeps) is not high enough. In addition, comparative analysis with the existing models of h...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamori, Daiki, Akamine, Hiroki, Takayama, Kazuo, Sakurai, Fuminori, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709502/
https://www.ncbi.nlm.nih.gov/pubmed/29192290
http://dx.doi.org/10.1038/s41598-017-16856-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709502/
https://www.ncbi.nlm.nih.gov/pubmed/29192290
http://dx.doi.org/10.1038/s41598-017-16856-7

Ejemplares similares