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Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy

ATG5 and ATG7 are considered to be essential molecules for the induction of autophagy. However, we found that cells lacking ATG5 or ATG7 can still form autophagosomes/autolysosomes and perform autophagic protein degradation when subjected to certain types of stress. Although the lipidation of LC3 is...

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Detalles Bibliográficos
Autores principales: ARAKAWA, Satoko, HONDA, Shinya, YAMAGUCHI, Hirofumi, SHIMIZU, Shigeomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709538/
https://www.ncbi.nlm.nih.gov/pubmed/28603209
http://dx.doi.org/10.2183/pjab.93.023