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RNA-Seq Analysis of Differentiated Keratinocytes Reveals a Massive Response to Late Events during Human Papillomavirus 16 Infection, Including Loss of Epithelial Barrier Function

The human papillomavirus (HPV) replication cycle is tightly linked to epithelial cell differentiation. To examine HPV-associated changes in the keratinocyte transcriptome, RNAs isolated from undifferentiated and differentiated cell populations of normal, spontaneously immortalized keratinocytes (NIK...

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Detalles Bibliográficos
Autores principales: Klymenko, T., Gu, Q., Herbert, I., Stevenson, A., Iliev, V., Watkins, G., Pollock, C., Bhatia, R., Cuschieri, K., Herzyk, P., Gatherer, D., Graham, S. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709591/
https://www.ncbi.nlm.nih.gov/pubmed/29021401
http://dx.doi.org/10.1128/JVI.01001-17