DR5‐Cbl‐b/c‐Cbl‐TRAF2 complex inhibits TRAIL‐induced apoptosis by promoting TRAF2‐mediated polyubiquitination of caspase‐8 in gastric cancer cells

Ubiquitination of caspase‐8 regulates TNF‐related apoptosis‐inducing ligand (TRAIL) sensitivity in cancer cells, and the preligand assembly complex plays a role in caspase‐8 polyubiquitination. However, whether such a complex exists in gastric cancer cells and its role in TRAIL‐triggered apoptosis i...

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Detalles Bibliográficos
Autores principales: Xu, Ling, Zhang, Ye, Qu, Xiujuan, Che, Xiaofang, Guo, Tianshu, Li, Ce, Ma, Rui, Fan, Yibo, Ma, Yanju, Hou, Kezuo, Li, Danni, Hu, Xuejun, Liu, Bofang, Yu, Ruoxi, Yan, Hongfei, Gong, Jing, Liu, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709619/
https://www.ncbi.nlm.nih.gov/pubmed/28972304
http://dx.doi.org/10.1002/1878-0261.12140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709619/
https://www.ncbi.nlm.nih.gov/pubmed/28972304
http://dx.doi.org/10.1002/1878-0261.12140

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