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Role of Brf1 interaction with ERα, and significance of its overexpression, in human breast cancer

TFIIB‐related factor 1 (Brf1) modulates the transcription of RNA Pol III genes (polymerase‐dependent genes). Upregulation of Pol III genes enhances tRNA and 5S RNA production and increases the translational capacity of cells to promote cell transformation and tumor development. However, the signific...

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Detalles Bibliográficos
Autores principales: Fang, Zeng, Yi, Yunfeng, Shi, Ganggang, Li, Songqi, Chen, Songlin, Lin, Ying, Li, Zhi, He, Zhimin, Li, Wen, Zhong, Shuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709663/
https://www.ncbi.nlm.nih.gov/pubmed/28972307
http://dx.doi.org/10.1002/1878-0261.12141