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Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis

Tuberculosis (TB) is known to be affected by host genetic factors. We reported a specific genetic risk factor through a genome-wide association study (GWAS) that focused on young age onset TB. In this study, we further focused on the heterogeneity of Mycobacterium tuberculosis (M. tb) lineages and a...

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Detalles Bibliográficos
Autores principales: Omae, Yosuke, Toyo-oka, Licht, Yanai, Hideki, Nedsuwan, Supalert, Wattanapokayakit, Sukanya, Satproedprai, Nusara, Smittipat, Nat, Palittapongarnpim, Prasit, Sawanpanyalert, Pathom, Inunchot, Wimala, Pasomsub, Ekawat, Wichukchinda, Nuanjun, Mushiroda, Taisei, Kubo, Michiaki, Tokunaga, Katsushi, Mahasirimongkol, Surakameth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709719/
https://www.ncbi.nlm.nih.gov/pubmed/28878339
http://dx.doi.org/10.1038/jhg.2017.82