Real‐time detection of condensin‐driven DNA compaction reveals a multistep binding mechanism

Condensin, a conserved member of the SMC protein family of ring‐shaped multi‐subunit protein complexes, is essential for structuring and compacting chromosomes. Despite its key role, its molecular mechanism has remained largely unknown. Here, we employ single‐molecule magnetic tweezers to measure, i...

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Detalles Bibliográficos
Autores principales: Eeftens, Jorine M, Bisht, Shveta, Kerssemakers, Jacob, Kschonsak, Marc, Haering, Christian H, Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709735/
https://www.ncbi.nlm.nih.gov/pubmed/29118001
http://dx.doi.org/10.15252/embj.201797596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709735/
https://www.ncbi.nlm.nih.gov/pubmed/29118001
http://dx.doi.org/10.15252/embj.201797596

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