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Isoform‐specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands
DNA methylation is a prevalent epigenetic modification involved in transcriptional regulation and essential for mammalian development. While the genome‐wide distribution of this mark has been studied to great detail, the mechanisms responsible for its correct deposition, as well as the cause for its...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709737/ https://www.ncbi.nlm.nih.gov/pubmed/29074627 http://dx.doi.org/10.15252/embj.201797038 |