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Molecular basis for inner kinetochore configuration through RWD domain–peptide interactions

Kinetochores are dynamic cellular structures that connect chromosomes to microtubules. They form from multi‐protein assemblies that are evolutionarily conserved between yeasts and humans. One of these assemblies—COMA—consists of subunits Ame1(CENP‐U), Ctf19(CENP‐P), Mcm21(CENP‐O) and Okp1(CENP‐Q). A...

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Detalles Bibliográficos
Autores principales: Schmitzberger, Florian, Richter, Magdalena M, Gordiyenko, Yuliya, Robinson, Carol V, Dadlez, Michał, Westermann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709738/
https://www.ncbi.nlm.nih.gov/pubmed/29046335
http://dx.doi.org/10.15252/embj.201796636