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Meis2 as a critical player in MN1-induced leukemia

Meningioma 1 (MN1) is an independent prognostic marker for normal karyotype acute myeloid leukemia (AML), with high expression linked to all-trans retinoic acid resistance and poor survival. MN1 is also a potent and sufficient oncogene in murine leukemia models, strongly dependent on the MEIS1/AbdB-...

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Detalles Bibliográficos
Autores principales: Lai, C K, Norddahl, G L, Maetzig, T, Rosten, P, Lohr, T, Sanchez Milde, L, von Krosigk, N, Docking, T R, Heuser, M, Karsan, A, Humphries, R K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709755/
https://www.ncbi.nlm.nih.gov/pubmed/28960191
http://dx.doi.org/10.1038/bcj.2017.86