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Meis2 as a critical player in MN1-induced leukemia
Meningioma 1 (MN1) is an independent prognostic marker for normal karyotype acute myeloid leukemia (AML), with high expression linked to all-trans retinoic acid resistance and poor survival. MN1 is also a potent and sufficient oncogene in murine leukemia models, strongly dependent on the MEIS1/AbdB-...
Autores principales: | Lai, C K, Norddahl, G L, Maetzig, T, Rosten, P, Lohr, T, Sanchez Milde, L, von Krosigk, N, Docking, T R, Heuser, M, Karsan, A, Humphries, R K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709755/ https://www.ncbi.nlm.nih.gov/pubmed/28960191 http://dx.doi.org/10.1038/bcj.2017.86 |
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