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Protonation Enhances the Inherent Helix-Forming Propensity of pHLIP
[Image: see text] Cell-penetrating peptides (CPPs) can be potentially used in targeted delivery of therapeutic cargoes. However, their conformation in solution is poorly understood. We employed molecular dynamics simulations to probe the structural fluctuations of an anionic CPP, pH Low Insertion Pe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709774/ https://www.ncbi.nlm.nih.gov/pubmed/29214239 http://dx.doi.org/10.1021/acsomega.7b01371 |