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Multistep Conformation Selection in Amyloid Assembly
[Image: see text] Defining pathways for amyloid assembly could impact therapeutic strategies for as many as 50 disease states. Here we show that amyloid assembly is subject to different forces regulating nucleation and propagation steps and provide evidence that the more global β-sheet/β-sheet facia...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709775/ https://www.ncbi.nlm.nih.gov/pubmed/29111722 http://dx.doi.org/10.1021/jacs.7b09362 |