Redox Regulation of a Gain-of-Function Mutation (N308D) in SHP2 Noonan Syndrome

[Image: see text] SHP2 (Src homology 2 domain-containing protein tyrosine phosphatase 2; PTPN11) is a ubiquitous multidomain, nonreceptor protein tyrosine phosphatase (PTP) that plays an important role in diseases such as cancer, diabetes, and Noonan syndrome (NS). NS is one of the most common genet...

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Detalles Bibliográficos
Autores principales: Machado, Luciana E. S. F., Critton, David A., Page, Rebecca, Peti, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709778/
https://www.ncbi.nlm.nih.gov/pubmed/29214238
http://dx.doi.org/10.1021/acsomega.7b01318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709778/
https://www.ncbi.nlm.nih.gov/pubmed/29214238
http://dx.doi.org/10.1021/acsomega.7b01318

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