CiAPEX2 and CiP0, candidates of AP endonucleases in Ciona intestinalis, have 3′-5′ exonuclease activity and contribute to protection against oxidative stress

Apurinic/apyrimidinic (AP) sites are one of the most frequent DNA lesions. AP sites inhibit transcription and DNA replication, and induce cell death. AP endonucleases are key enzymes in AP site repair. Several types of AP endonucleases have been reported, such as AP endonuclease 2 (APEX2) and riboso...

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Detalles Bibliográficos
Autores principales: Funakoshi, Masafumi, Nambara, Daisuke, Hayashi, Yuichiro, Zhang-Akiyama, Qiu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709841/
https://www.ncbi.nlm.nih.gov/pubmed/29213341
http://dx.doi.org/10.1186/s41021-017-0087-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709841/
https://www.ncbi.nlm.nih.gov/pubmed/29213341
http://dx.doi.org/10.1186/s41021-017-0087-7

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