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Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients

BACKGROUND: SHOX2 and SEPT9 methylation in circulating cell-free DNA (ccfDNA) in blood are established powerful and clinically valuable biomarkers for diagnosis, staging, prognosis, and monitoring of cancer patients. The aim of the present study was to evaluate different quantification algorithms (r...

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Detalles Bibliográficos
Autores principales: de Vos, Luka, Gevensleben, Heidrun, Schröck, Andreas, Franzen, Alina, Kristiansen, Glen, Bootz, Friedrich, Dietrich, Dimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709918/
https://www.ncbi.nlm.nih.gov/pubmed/29213339
http://dx.doi.org/10.1186/s13148-017-0425-4