OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps

We present a new method, OMSV, for accurately and comprehensively identifying structural variations (SVs) from optical maps. OMSV detects both homozygous and heterozygous SVs, SVs of various types and sizes, and SVs with or without creating or destroying restriction sites. We show that OMSV has high...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Le, Leung, Alden King-Yung, Kwok, Tsz-Piu, Lai, Yvonne Y. Y., Pang, Iris K., Chung, Grace Tin-Yun, Mak, Angel C. Y., Poon, Annie, Chu, Catherine, Li, Menglu, Wu, Jacob J. K., Lam, Ernest T., Cao, Han, Lin, Chin, Sibert, Justin, Yiu, Siu-Ming, Xiao, Ming, Lo, Kwok-Wai, Kwok, Pui-Yan, Chan, Ting-Fung, Yip, Kevin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709945/
https://www.ncbi.nlm.nih.gov/pubmed/29195502
http://dx.doi.org/10.1186/s13059-017-1356-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709945/
https://www.ncbi.nlm.nih.gov/pubmed/29195502
http://dx.doi.org/10.1186/s13059-017-1356-2

Ejemplares similares